Date:
January 6, 2022
Amy Chen (Student)
“Outsmarting the immune system: inactivation of the miRNA machinery protects tumor cells from T-cell mediated cytotoxicity"
Song, TY., Long, M., Zhao, HX. et al. Tumor evolution selectively inactivates the core microRNA machinery for immune evasion. Nat Commun 12, 7003 (2021)
Coaches: Melissa Reeves, PhD & Robert Blelloch, MD, PhD
Hanson Tam (Student)
"B cells unTEThered, lymphoma unleashed"
Shukla, V., Samaniego-Castruita, D., Dong, Z. et al. TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures. Nat Immunol 23, 99–108 (2022).
Coaches: Jason Cyster, PhD & Mark Ansel, PhD