BMS Journal Club

2017-18 Journal Club Schedule

Dates: September 2017-June 2018

Journal Club Chairs: Bruce Wang, MD and Tien Peng, MD
Day/Time: Thursdays, 12:00-1:00 p.m. except as noted
Location: N-225, Parnassus & videoconferenced to Room MH-1405, Mission Bay.
Links to the live stream and recorded video are in the sidebar.


**If you're watching the video stream at Mission Bay and would like to ask the speaker a question, send a DM via Twitter to @UCSF_BMS_JC and someone at Parnassus will ask your question for you.


See the BMS Journal Club Archives in the right sidebar for past years' journal clubs.


September 7, 2017

Saul Villeda, PhD (Faculty)
"High as a Kite: Making the Old Brain Young Again?"
Bilkei-Gorzo, Andras et al. "A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice." Nature Medicine 23, 782–787 (2017).​

Alexis Krup (Student)
“The Crypt Keepers: a story of secret stem cells, as told by their chromatin”
Jadhav, Unmesh et al. “Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells.” Cell Stem Cell 21.1 (2016): 65–77.e5.
Coaches: Miguel Ramalho-Santos and Robert Blelloch

Mission Bay videoconference: MH-1405


September 14, 2017

Joseph Shieh, MD, PhD (Faculty)
"Are we heterogeneous or homogeneous? Natural variation, mutation, and disease"
Florian Zink et al. "Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly." Blood , no. (2017): blood-2017-02-769869.​

Patrick Schupp (Student)
A Glioma miR-acle: miR128 drives Class Shift in Glioblastoma Stem-like Cells
Rooj, A. K. et al. MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells. Cell Rep. 19, 2026–2032 (2017).
Coaches: Michael Oldham and Samuel Shelton

Mission Bay videoconference: MH-1405


September 21, 2017

JJ Miranda, PhD (Faculty)
“Redefining viral infection during cancer”
Yogev O, Henderson S, Hayes MJ, Marelli SS, Ofir-Birin Y, Regev-Rudzki N, et al. (2017) Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs. PLoS Pathog 13(8): e1006524.

Jerika Barron (Student)
"Stop interferon’ with my synapses! IFN drives microglia-dependent synapse loss in CNS lupus"
Bialas, A. R. et al. Microglia-dependent synapse loss in type I interferon-mediated lupus. Nature 546, 539–543 (2017).
Coaches: Anna Molofsky and Susanna Rosi

Mission Bay videoconference: MH-1405


September 28, 2017

Aaron Tward, MD, PhD (Faculty)
"The DRIVE to find Achilles’ heels of cancer: shRNA works great … if you have 100,000 of them."
Tsherniak A. et al. "Defining a Cancer Dependency Map." Cell, 170(3):564-576.e16. 2017.
McDonald E.R. et al. "Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening." Cell 170(3):577-592.e10. 2017.

Johnny Yu (student)
"Hi, my name is Cancer and I'm an exosome-oholic."
Nabet, B.Y. et al. "Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer." Cell, Volume 170 (2), 352-366. 2017.
Coaches: Hani Goodarzi and Luke Gilbert

Mission Bay videoconference: MH-1405


October 5, 2017

Laura van 't Veer, PhD (Faculty)
"Chemotherapy indices metastasis, ‘of mice to (wo-)men"
Karagiannis, George et al. “Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.” Science Translation Medicine 05 Jul 2017: Vol. 9, Issue 397

Geil Merana (student)
"New Cell on the Block"
Wang S. et al. "Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation." Cell 171 (1), 201-216. 2017 Aug 24.
Coaches: Tiffany Scharschmidt and Ari Molofsky

Mission Bay videoconference: MH-1405


October 12, 2017

Raymond Swanson, MD (Faculty)
"Et tu, dopamine?"
Mor, D.E. et al. "Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration." Nature Neuroscience (2017).

Katerina Popova (Student)
"Don't get antsy...CRISPR-engineered ants are already here!"
Hua, Y. et al. An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants. Cell 170(4), 736-747, 10 Aug 2017.
Coaches: Stephen Floor and Luke Gilbert

Mission Bay videoconference: MH-1405


October 19, 2017

Arun Wiita, MD, PhD (Faculty)
"It's ok to judge a tumor by its cover"
Bosse KR et al. Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma. Cancer Cell (2017) 32:295.​

Anthony Venida (Student)
"The Sidekick Tale of an Immune Checkpoint Regulator: CMTM6 is to PD-L1 as Robin is to Batman"
Burr, Marian L. et al. "CMTM6 Maintains the Expression of PD-LI and Regulates Anti-Tumor Immunity." Nature 549, 101-105 (2017).
Coaches: Rushika Perera and Matthew Spitzer

Mission Bay videoconference: MH-1405


October 26, 2017

Aditi Bhargava, PhD (Faculty)
"Sex or Gender: Scoop on COUP-TFII"
Zhao, F. et al. "Elimination of the male reproductive tract in the femal embryo is promoted by COUP-TFII in mice." Science, 357, 6352, 717-720. 18 Aug 2017.​

Karen Wong (Student)
"Most wanted: missing sequences in the reference genome"
Kehr B. et al. “Diversity in non-repetitive human sequences not found in the reference genome.” Nature genetics. 49, 588-593. 2017 Feb 27.
Coaches: Joseph Shieh and Marina Sirota

Mission Bay videoconference: MH-1405


November 2, 2017

Seemay Chou, PhD (Faculty)
Title TBA
Jeremy Williams (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


November 9, 2017

Stephen Floor, PhD (Faculty)
Title: "To PB or not to PB: Condensed Granules of RNA Regulons"
Hubstenberger, A. et al. "P-Body Purification Reveals the Condensation of Repressed mRNA Regulons" Molecular Cell 68, 1-14 (2017).

Elma Frias (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


November 16, 2017

Rushika Perera, PhD (Faculty)
Title TBA

Nicholas Gentry (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


November 30, 2017

Andy Chang, PhD (Faculty)
Title TBA

Jeanmarie Gonzalez (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


December 7, 2017

Diana Laird, PhD (Faculty)
Title TBA

Didi Zhu (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


January 11, 2018

Robert Nissenson, PhD (Faculty)
Title TBA

Kamir Hiam (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


January 18, 2018

Elise Wolf (Student)
Title TBA
Coaches: TBA

Sara Sunshine (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


January 25, 2018

*Note: BMS Interview Day, Journal Club takes place at 5:00pm.

Faculty TBA

Title TBA

Breanna Allen (Student)
Title TBA
Coaches TBA

Mission Bay videoconference: MH-1405


February 1, 2018

Katharine Yu (Student)
Title TBA
Coaches: TBA

Nikolai Zapero (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


February 8, 2018

*Note: BMS Interview Day, Journal Club takes place at 5:00pm.

Faculty TBA

Title TBA

Ramiro Patino (Student)
Title TBA
Coaches TBA

Mission Bay videoconference: MH-1405


February 15, 2018

Jiapei Chen (Student)
Title TBA
Coaches: TBA

Devan Diwanji (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


February 22, 2018

Camille Simoneau (Student)
Title TBA
Coaches: TBA

Austin Hsu (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


March 1, 2018

Camillia Azimi (Student)
Title TBA
Coaches: TBA

Cassandra Burnett (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


March 8, 2018

Karen Chan (Student)
Title TBA
Coaches: TBA

Irene Chen (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


March 15, 2018

Tyler Fair (Student)
Title TBA
Coaches: TBA

Antonia Gallman (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


March 22, 2018

Lauren McHenry (Student)
Title TBA
Coaches: TBA

Kristoffer Leon (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


March 29, 2018

Ian Boothby (Student)
Title TBA
Coaches: TBA

Paul Wei (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


April 5, 2018

Isobel Hawes (Student)
Title TBA
Coaches: TBA

Kun Leng (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


April 12, 2018

Elizabeth Hwang (Student)
Title TBA
Coaches: TBA

David Shin (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


April 19, 2018

Naznin Jahan (Student)
Title TBA
Coaches: TBA

Kyle Kisor (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


April 26, 2018

Emmy Li (Student)
Title TBA
Coaches: TBA

Nicholas Stevers (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


May 3, 2018

Tara McIntyre (Student)
Title TBA
Coaches: TBA

Catherine Tan (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


May 10, 2018

Rachel Nakagawa (Student)
Title TBA
Coaches: TBA

Jennifer Umhoefer (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


May 17, 2018

Maxine Nelson (Student)
Title TBA
Coaches: TBA

Kevin Wilkins (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


May 24, 2018

Lindsey Pieper (Student)
Title TBA
Coaches: TBA

Fauna Yarza (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


May 31, 2018

Donovan Trinidad (Student)
Title TBA
Coaches: TBA

Ryan Ziffra (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405


June 7, 2018

Yuhao Wang (Student)
Title TBA
Coaches: TBA

Denise Allen (Student)
Title TBA
Coaches: TBA

Mission Bay videoconference: MH-1405