Alzheimer's & Dementia

Machine Learning Approach to Identify Dysregulation in the Plasma Proteome of CADASIL.

Alzheimer's & Dementia

Jonah Keller, Stephen Fitzsimons, Ryan Park, Luana Moury, Bradley C Oh, Scott Treiman, Hannah Radabaugh, Adam Ferguson, Fanny M Elahi

Machine Learning Approach to Identify Dysregulation in the Plasma Proteome of CADASIL.

Alzheimer's & Dementia

Jonah Keller, Stephen Fitzsimons, Ryan Park, Luana Moury, Bradley C Oh, Scott Treiman, Hannah Radabaugh, Adam Ferguson, Fanny M Elahi

Plasma rejuvenation factor GDF11 associates with amyloid-related cognitive decline in older adults across the Alzheimer’s Disease spectrum.

Alzheimer's & Dementia

Shannon Y. Lee, Emily W. Paolillo, Rowan Saloner, Anna M VandeBunte, Gil D. Rabinovici, Renaud La Joie, Joel H. Kramer, Saul Villeda, Kaitlin B. Casaletto

Relationships between KLOTHO and APOE4-associated ß-amyloid and tau alterations across AD continuum.

Alzheimer's & Dementia

Noah R. Cook, Ira Driscoll, Catherine L. Gallagher, Sterling C Johnson, Sanjay Asthana, Bruce P Hermann, Mark A. Sager, Kaj Blennow, Henrik Zetterberg, Cynthia M. Carlsson, Gwendlyn Kollmorgen, Margherita Carboni, Dan Wang, Dena B. Dubal, Ozioma Okonkwo

Klotho protein concentrations as a function of sex, APOE, family history or Alzheimer’s disease biomarker status in an at-risk cohort.

Alzheimer's & Dementia

Ira Driscoll, Tobey J Betthauser, Catherine L. Gallagher, Bruce P Hermann, Mark A. Sager, Cynthia M. Carlsson, Gwendlyn Kollmorgen, Margherita Carboni, Dan Wang, Kaj Blennow, Henrik Zetterberg, Sterling C Johnson, Sanjay Asthana, Dena B. Dubal, Ozioma Okonkwo

Transcriptomic Profiling Across Age, APOE and Sex for Models of Alzheimer’s Disease at a Single Cell Resolution.

Alzheimer's & Dementia

Yaqiao Li, Yanxia Hao, Seo Yeon Yoon, Brian Grone, Leonardo Ding, Jessica Blumenfeld, Tomiko Oskotsky, Yadong Huang, Marina Sirota

Predictive Modeling Leveraging Electronic Health Records Identifies Early Predictors of Alzheimer’s Disease.

Alzheimer's & Dementia

Alice S Tang, Katherine P Rankin, Gabriel Cerano, Silvia Miramontes, Hunter Mills, Tomiko Oskotsky, Billy Zeng, Charlotte Nelson, Karthik Soman, Sarah Woldemariam, Yaqiao Li, Albert M Lee, Zachary Miller, Isabel Elaine Allen, Stephan Sanders, Sergio Baranzini, Marina Sirota

Phospholipase D3 drives microglial response to amyloid pathology in Alzheimer’s disease.

Alzheimer's & Dementia

Matthew J Rosene, Emma Danhash, Shih-Feng You, Abhirami Kannan Iyer, Simon Hsu, Mariana Acquarone de Sa Lopes, Logan Brase, Anthony Verbeck, Rita Martinez, Clare E Wallace, Zeran Li, Ping Yan, Nina Drager, Sydney M Sattler, Thomas E Mahan, Shannon L Macauley, David M. Holtzman, Bruno A. Benitez, Martin Kampmann, Carlos Cruchaga, Oscar Harari, John R Cirrito, Jin-Moo Lee, Alison Goate, Celeste M. Karch

Multiomics of iPSC-derived ApoE3- and ApoE4 astrocytes and microglia uncovers cell type specific dysregulation of immunometabolism.

Alzheimer's & Dementia

Rik van der Kant, Niek Blomberg, Lena Erlebach, Femke M Feringa, Jorin Heijneman, Sascha Koppes, Iris Daphne Kruijff, Amanda McQuade, Ricardo Miramontes, Damien Olivier-Jimenez, Aiko Robert, Leslie M. Thompson, Alessandro Ori, Deborah Kronenberg-Versteeg, Yassene Mohammed, Martin Kampmann, Martin Giera

Alzheimer’s disease risk genes modulate interferon-responsive microglia.

Alzheimer's & Dementia

Amanda McQuade, Vincent Cele Castillo, Nina Drager, Martin Kampmann

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