Michael Wilson, MD

Professor
UCSF Weill Institute for Neurosciences
Department of Neurology
Primary Thematic Area
Virology & Microbial Pathogenesis
Secondary Thematic Area
Immunology
Research Summary
Genomic approaches to identifying causes and understanding the pathogenesis of autoimmune and infectious neuroinflammatory conditions including encephalitis, meningitis and multiple sclerosis, and developing cell-based therapies for treatment.
Mentorship Development

5/2021 - Sharpening your Mentoring Skills (SyMS)

[email protected]
415-502-7429

I am a neurologist specializing in infectious and autoimmune diseases of the central nervous system. I see patients with autoimmune diseases like multiple sclerosis and autoimmune encephalitis as well as patients with a wide array of infectious diseases that impact the nervous system like HIV, neurocysticercosis, neurosyphilis, viral encephalitis and fungal infections. My laboratory applies metagenomic and immune repertoire sequencing techniques as well as phage display antibody discovery technologies to enhance our understanding of the causes and immunopathogenesis of multiple sclerosis as well as autoimmune and infectious causes of meningoencephalitis.

Publications

Integrating central nervous system metagenomics and host response for diagnosis of tuberculosis meningitis and its mimics.

Nature communications

Ramachandran PS, Ramesh A, Creswell FV, Wapniarski A, Narendra R, Quinn CM, Tran EB, Rutakingirwa MK, Bangdiwala AS, Kagimu E, Kandole KT, Zorn KC, Tugume L, Kasibante J, Ssebambulidde K, Okirwoth M, Bahr NC, Musubire A, Skipper CP, Fouassier C, Lyden A, Serpa P, Castaneda G, Caldera S, Ahyong V, DeRisi JL, Langelier C, Crawford ED, Boulware DR, Meya DB, Wilson MR

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis.

The New England journal of medicine

Wilson MR, Sample HA, Zorn KC, Arevalo S, Yu G, Neuhaus J, Federman S, Stryke D, Briggs B, Langelier C, Berger A, Douglas V, Josephson SA, Chow FC, Fulton BD, DeRisi JL, Gelfand JM, Naccache SN, Bender J, Dien Bard J, Murkey J, Carlson M, Vespa PM, Vijayan T, Allyn PR, Campeau S, Humphries RM, Klausner JD, Ganzon CD, Memar F, Ocampo NA, Zimmermann LL, Cohen SH, Polage CR, DeBiasi RL, Haller B, Dallas R, Maron G, Hayden R, Messacar K, Dominguez SR, Miller S, Chiu CY

Pan-viral serology implicates enteroviruses in acute flaccid myelitis.

Nature medicine

Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GA, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR