Raymond Swanson, MD

Professor
Department of Neurology
+1 415 575-0403

Raymond A. Swanson graduated from the University of Michigan Medical School and completed Neurology residency training at UCSF. He subsequently completed post-doctoral research fellowships at UCSF and Stanford University. He is currently chief of the Neurology service at the San Francisco Veterans Affairs Medical Center, and heads a research lab located on the UCSF Mission Bay campus.

His research focus is on bioenergetics and oxidative signaling in neurological disease. Studies in the area of stroke aim to identify ways to mitigate the dendritic and axonal ischemic injury caused by neuronal NADPH oxidase and formation of cofilin rods. Work pertaining to Parkinson's disease aims to identify interactions between neuronal redox state and alpha-synuclein aggregation. This effort also involves pre-clinical and clinical studies of thiol repletion agents as a disease-modifying therapeutic approach.

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
None
Research Summary: 
Bioenergetics and oxidative signaling in neurological disease

Websites

Publications: 

Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP.

Nature communications

Shen Y, Kapfhamer D, Minnella AM, Kim JE, Won SJ, Chen Y, Huang Y, Low LH, Massa SM, Swanson RA

A data-driven approach for evaluating multi-modal therapy in traumatic brain injury.

Scientific reports

Haefeli J, Ferguson AR, Bingham D, Orr A, Won SJ, Lam TI, Shi J, Hawley S, Liu J, Swanson RA, Massa SM

Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration.

eLife

Ko HR, Kwon IS, Hwang I, Jin EJ, Shin JH, Brennan-Minnella AM, Swanson R, Cho SW, Lee KH, Ahn JY

Neuronal Glutathione Content and Antioxidant Capacity can be Normalized In Situ by N-acetyl Cysteine Concentrations Attained in Human Cerebrospinal Fluid.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Reyes RC, Cittolin-Santos GF, Kim JE, Won SJ, Brennan-Minnella AM, Katz M, Glass GA, Swanson RA