Normal and malignant blood cell development, including break of immune tolerance (autoimmunity) and blood cell cancer (leukemia), with a focus on transcriptional regulation.
Mentorship Development:
12/12/19 ACRA: Setting Training Expectations for Trainees on the Academic Career Track (1.5 hours)
3/3/20 Promoting Student Mental Health:A Presentation and Discussion (Staff and Faculty)
3/3/20 Promoting Student Mental Health: Faculty Workshop (Faculty only)
4/23/20 Effective Strategies for IDPs
11/10/20 Optimizing the Efficiency of Your Lab
2/18/21 Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels
We are molecularly modifying pluripotent stem cell lines to create non-immunogenic cells that are protected from post-transplant rejection without affecting the general immune system.
4/11/19 Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Mission Bay)
2/16/21 Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels
We study T cell immunity to tuberculosis (TB). In mice, we characterize mechanisms of CD4 T cell evasion in TB, and we study humans to discover mechanisms that provide protective immunity to TB that can be improved by vaccines.
Our program explores the impact of metabolic stress on deregulated micro-RNA controlled hematopoiesis and immune cell function in the pathogenesis of atherosclerosis, including through intercellular signaling via exosomes
Our lab applies single-cell analysis approaches on in vitro and clinical specimens to study the interplay between immune cells & viral pathogens including HIV & SARS-CoV-2, & to study the properties of immune cells in mucosal tissues in health & disease
Immunmodulatory, cytoreductive chemotherapeutic and stem cell transplantation approaches to HIV-1 cure. Design and implementation of novel nano/microtechnologies to characterize viral reservoirs.
Immune mechanisms that support host-commensal symbiosis
Mentorship Development:
11/23/20 Building Community in the UCSF MSTP
2/16/21 Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels
Dr. Butte builds and applies tools that convert more than 400 trillion points of molecular, clinical, and epidemiological data into diagnostics, therapeutics, and new insights into disease.
