Cancer Biology & Cell Signaling

Rongze Lu, PhD

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Identify underlying mechanisms of brain tumor immunosuppression and evasion, with the goal to develop novel immunotherapies for brain cancer.

Julia Carnevale, MD

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Our group uses novel gene engineering strategies to decode key genetic programs that we can target to rewire immune cells into effective cancer treatments.

Karin Pelka, PhD

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Using single cell genomics and tissue imaging, we study the cellular interactions that shape immune responses in human tumors in order to harness the immune system in the fight against cancer.

John Gordan, MD, PhD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
None
Research Summary: 
The Gordan lab combines chemical biology with cancer systems biology strategies to identify new therapeutic targets and drug combinations for GI cancers.

Alexis Combes, PhD

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Discover and dissect recurring patterns of the immune system.

Javid Moslehi, MD

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Using Cardio-Oncology and Cardio-Immunology as platforms to understand cardiovascular signaling

Vijay Ramani, PhD

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Our lab develops new genome-scale methods to study mammalian chromatin structure and transcriptional regulation

Justin Eyquem, PhD, MS, BS

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
We are designing synthetic receptors and editing the T cell’s genome to better understand T cells function within the tumor microenvironment and ultimately design safe and efficient adoptive T cell therapies

Daniel Mordes, MD, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Mechanisms of Neurodegeneration in ALS and Dementia

Jennifer Chen, MD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Dr. Jennifer Y. Chen’s research program focuses on the development of novel antifibrotic therapies and biomarkers for patients with chronic liver disease.

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