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Vascular & Cardiac Biology

Submitted by admin on Mon, 2010-08-09 14:02

Stenotic Aortic Valve Section (Photo by Mark White and Deepak Srivastava, MD)Opportunities abound for research training in Vascular and Cardiac Biology.

UCSF's Cardiovascular Research Institute (CVRI) both provides a home for such research and fosters interactions among investigators throughout UCSF who are interested in cardiovascular biology and disease. The spectrum of investigation ranges from basic structural and chemical biology through cell biology, signaling and invertebrate and vertebrate models of cardiovascular development and disease to human genetics and patient-based disease research.  CVRI faculty are represented on all UCSF campuses save Mt. Zion with concentrations on Parnassus and in the new Smith Cardiovascular Research Building at Mission Bay.

The Gladstone Institute of Cardiovascular Disease (GICD) is located at Gladstone's new research facility adjacent to UCSF's Mission Bay campus. While independent, Gladstone is formally affiliated with UCSF, and Gladstone investigators hold university appointments and participate in many university activities, including the teaching and training of graduate students. GICD's mission is to contribute to the health and welfare of humankind through research into the causes and prevention of cardiovascular disease.

Participating Faculty
Manish Aghi, MD, PhD
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Vascular & Cardiac Biology
Defining the interaction between tumor cells and the microenvironment in glioblastoma, including during therapeutic resistance
Gabriele Bergers, PhD
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Vascular & Cardiac Biology
Elucidating the dialogue between the tumor cell compartment and the vascular niche
Brian Black, PhD
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Vascular & Cardiac BiologyTranscriptional Control of Mammalian Organogenesis
Denise Chan, PhD
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Vascular & Cardiac BiologyUnderstanding tumor oxygen homeostasis and angiogenesis
Bruce Conklin, MD
Primary Research Interest: Vascular & Cardiac BiologySecondary Research Interest: Developmental & Stem Cell Biology

Receptors, Stem Cells and Pharmacology

Shaun Coughlin, MD, PhD
Primary Research Interest: Vascular & Cardiac BiologySecondary Research Interest: Cancer Biology & Cell SignalingSignaling mechanisms in cardiovascular biology and disease
Maximiliano DAngelo, PhD
Primary Research Interest: Vascular & Cardiac Biology
Rahul C. Deo, MD, PhD
Primary Research Interest: Human GeneticsSecondary Research Interest: Vascular & Cardiac BiologyComputational and cellular approaches to metabolic disease
Robert V. Farese Jr., MD
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Vascular & Cardiac Biology

Lipid homeostasis in cells and organisms

Susan Fisher, PhD
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Vascular & Cardiac BiologyPlacental Biology/Bacterial Adhesion
David Gardner, MD
Primary Research Interest: Vascular & Cardiac BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyEndocrine control of growth and function in the cardiovascular system: role of the natriuretic peptides and vitamin D
Douglas B. Gould, PhD
Primary Research Interest: Human GeneticsSecondary Research Interest: Vascular & Cardiac BiologyGenetic Dissection of Extracellular Matrix in Development and Disease
Carl Grunfeld, MD, PhD
Primary Research Interest: Vascular & Cardiac BiologySecondary Research Interest: ImmunologyMetabolic Changes and the Host Response to Infection
Hobart Harris, MD, MPH
Primary Research Interest: ImmunologySecondary Research Interest: Vascular & Cardiac BiologyLipoproteins and Immune Responses to Infection and Acute Injury
Akiko Hata, PhD
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Vascular & Cardiac BiologyTGFbeta family of signaling pathway
Judith Hellman, MD
Primary Research Interest: ImmunologySecondary Research Interest: Vascular & Cardiac BiologyRole of Innate Immune Pathways in Sepsis and Critical Illness
Lily Jan, PhD
Primary Research Interest: NeurobiologySecondary Research Interest: Vascular & Cardiac BiologyPotassium Channels
Natalia Jura, PhD
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Vascular & Cardiac BiologyMolecular basis for Receptor Tyrosine Kinase signaling across the plasma membrane
Jacquelyn Maher, MD
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Vascular & Cardiac BiologyTissue-protective cytokines; fatty liver disease
Takashi Mikawa, PhD
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Vascular & Cardiac BiologyDevelopmental Regulation of Organogenesis
Dan Minor, PhD
Primary Research Interest: NeurobiologySecondary Research Interest: Vascular & Cardiac BiologyMolecular Basis of Electrical Signaling
Jeffrey Olgin, MD
Primary Research Interest: Vascular & Cardiac BiologyMechanisms of cardiac arrhythmias
David Pearce, MD
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Vascular & Cardiac BiologyRegulation of gene expression and epithelial ion transport by stress steroids
Robin Shaw, MD, PhD
Primary Research Interest: Vascular & Cardiac BiologySecondary Research Interest: Cancer Biology & Cell SignalingRegulation of Cardiac Ion Channels: Cytoskeleton and Membrane Targeting
Matt Springer, PhD
Primary Research Interest: Vascular & Cardiac BiologyAngiogenesis & vascular biology, myocardial repair, endothelial function, and second hand smoke
Zena Vexler, PhD
Primary Research Interest: NeurobiologySecondary Research Interest: Vascular & Cardiac Biology
Brain microenvironment as modulator of neurovascular injury and repair after adult and neonatal stroke
Ethan J. Weiss, MD
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Vascular & Cardiac BiologyHormonal regulation of energy metabolism/ Novel mechanisms of thrombosis susceptibility
William L. Young, MD
Primary Research Interest: Vascular & Cardiac BiologySecondary Research Interest: Human GeneticsIntegrative Study of Brain Vascular Malformations
Ann Zovein, MD
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Vascular & Cardiac BiologyDiversification of vascular lineages