Tissue/Organ Biology & Endocrinology
The research of faculty in the areas of Tissue/Organ Biology & Endocrinology addresses biology at the level of the organism, moving from the molecular biology of the individual cell to integrated tissues, organs and organisms, and asking how this biology impacts human disease. UCSF has a long history in the biological sciences that relate to this area of research that is reflected in current Organized Research Units including the Center for Reproductive Sciences, Diabetes Center, Hormone Research Institute, Metabolic Unit, Liver Center, Cardiovascular Research Institute, Lung Biology Center, and Gladstone Institutes.
Among the specific research topics pursued are the genetic basis of obesity, the role of extracellular matrix in regulating cell function, the biological basis of diabetes, reproductive biology, adrenal function, ion fluxes in skin and epithelium, and calcium homeostasis.
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Participating Faculty
Primary Research Interest: Human GeneticsSecondary Research Interest: Tissue/Organ Biology & EndocrinologyGene regulation and human disease
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Developmental & Stem Cell BiologySkeletal Cell Differentiation and Matrix Quality
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: NeurobiologyAnalysis of genetic and neuronal networks that regulate fat content
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: ImmunologyApoptotic cell and collagen clearance in health and disease
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: NeurobiologyGut-brain cross-talk: mediation by stress hormone system
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Tissue/Organ Biology & EndocrinologyRegulation of cellular differentiation and function by calciotropic hormones
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Cancer Biology & Cell SignalingRole of Homeobox genes in cancer, angiogenesis and wound healing
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyIntracellular Membrane Traffic: Mechanisms & Immune Function
Primary Research Interest: Human GeneticsSecondary Research Interest: Tissue/Organ Biology & EndocrinologyGenetics approaches to study of the biology of the liver in health and disease
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyLung Peptidases in Allergy and Host Defense
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyImmune determinants of metabolism and regeneration
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Tissue/Organ Biology & EndocrinologyThe Role and Regulation of Autophagy in Epithelial Homeostasis and Cancer
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Tissue/Organ Biology & EndocrinologyMechanics of chromosome segregation
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyImmunopathogenesis of Asthma; Genomics of Disease
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyMechanism Oriented Clinical Research in Airway Disease
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Vascular & Cardiac BiologyCellular Lipid and Energy Metabolism
Primary Research Interest: NeurobiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyInjury Response in the Developing Nervous System
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Cancer Biology & Cell SignalingAlveolar epithelial barrier regulation and repair in the lung
Primary Research Interest: Vascular & Cardiac BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyEndocrine control of growth and function in the cardiovascular system: role of the natriuretic peptides and vitamin D
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyDevelopment and Biology of the Pancreatic Islets
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyNormal and abnormal endometrial development
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Developmental & Stem Cell BiologyHormonal and genetic regulation of human disease
Primary Research Interest: Human GeneticsSecondary Research Interest: Tissue/Organ Biology & EndocrinologyGenetic epidemiology of aging- and metabolism-related complex traits in humans
Primary Research Interest: Tissue/Organ Biology & EndocrinologyGrowth and Differentiated Function in Human Fetal Adrenal and Gonad
Primary Research Interest: Tissue/Organ Biology & EndocrinologyRole of the alveolar epithelium in lung fluid balance
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyMolecular Basis of Fat Cell Development and Energy Homeostasis
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: ImmunologyThe Intersection between Dietary Lipids, Inflammation, and Metabolic Disease
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: ImmunologyMechanisms of lung inflammation and injury
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Vascular & Cardiac BiologyTissue-protective cytokines; fatty liver disease
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyThe Regulation of Cell Fate by Oxygen and Mitochondria
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Developmental & Stem Cell BiologyIonic Fluxes Control Keratinocyte Adhesion, Differentiation and Secretion
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyEpithelial Polarity and Morphogenesis
Primary Research Interest: NeurobiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyMolecular Neurobiology of CNS Diseases
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Cancer Biology & Cell SignalingSignal Transduction Mechanisms in Bone Cell Differentiation and Function
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyStem Cells in the Drosophila Ovarian Epithelium
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Developmental & Stem Cell BiologyProtein misfolding diseases and novel therapies
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Vascular & Cardiac BiologyRegulation of gene expression and epithelial ion transport by stress steroids
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyRegulation of Stem Cell Pluripotency and Reprogramming
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyStem cells in lung development, maintenance and disease
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyCraniofacial Morphogenesis and Evolution
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyIn vivo function of integrins and molecular basis of lung diseases
Primary Research Interest: Tissue/Organ Biology & EndocrinologyParathyroid hormone secretion and physiology, calcium receptors, metabolic bone disease
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Tissue/Organ Biology & EndocrinologyRegulation of Genomic Instability in Mammalian Cells
Primary Research Interest: Human GeneticsSecondary Research Interest: Tissue/Organ Biology & EndocrinologyGenetics of Metabolic Diseases
Primary Research Interest: Developmental & Stem Cell BiologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyThe regulation of lung vascularization and development
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: Vascular & Cardiac BiologyHormonal regulation of energy metabolism/ Novel mechanisms of thrombosis susceptibility
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyCellular and molecular pathogenesis of lung disease
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: NeurobiologyHypothalamic regulation of energy balance, obesity and type 2 diabetes