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Immunology

Micrograph of an islet from a transgenic mouse expressing green fluorescent protein (GFP) in the pancreatic islet beta cells (courtesy Qizhi Tang, PhD)The UCSF Immunology Graduate Program is a component of both the Biomedical Sciences (BMS) program and the Program in Biological Sciences (PIBS). Currently, students interested in the program are admitted into the BMS program and elect to follow the Immunology Track at the end of the first year. First year BMS students pursue coursework with an emphasis on mammalian cells and tissues, including the immune system. Modern approaches for understanding the molecular mechanisms of cell, organ, and immune system function are studied as are integrative approaches toward defining the physiological in vivo importance of these mechanisms. We believe that this coursework will provide an excellent knowledge base for graduate students with a strong interest in immunology and related fields such as infectious disease. In addition, first year students do three research "rotations" in different BMS/Immunology laboratories to learn experimental approaches hands-on and to aid them in choosing a thesis laboratory and project. For students who elect the Immunology Track, the Immunology Graduate Program provides continuing advanced training in current developments of immunology and in other aspects of modern molecular and cellular biology via a weekly immunology student/faculty journal club, an annual immunology retreat, a yearly advanced topics seminar course, and a weekly seminar series by outstanding immunologists from around the U.S. and occasionally overseas. In addition to the above courses and activities, our connection with PIBS provides our students, postdoctoral fellows and faculty with close interactions with scientists studying cell biology, genetics, biochemistry and molecular biology, developmental biology, biophysics, and neuroscience. As these fields are highly relevant to modern study of immunology, these connections enhance the education of students in the Immunology Program.

Fall 2010 Courses:

Participating Faculty
Primary Research Interest: ImmunologyT-cell regulation in tolerance and immunity
Primary Research Interest: ImmunologySecondary Research Interest: Human GeneticsThe Genetic Control of Autoimmune Disease
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingRegulation of gene expression in the immune system
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: ImmunologyApoptotic cell and collagen clearance in health and disease
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisInnate and adaptive immunity to viral pathogens
Primary Research Interest: ImmunologySecondary Research Interest: Developmental & Stem Cell BiologyRegulation of T-cell activation and tolerance during autoimmune and transplantation responses
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyIntracellular Membrane Traffic: Mechanisms & Immune Function
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyLung Peptidases in Allergy and Host Defense
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingIntegrin signaling in lung fibrosis and cancer
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyImmune determinants of metabolism and regeneration
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyHost-Pathogen Interactions Responsible for M. tuberculosis Virulence
Primary Research Interest: Human GeneticsSecondary Research Interest: ImmunologyGenetics and epidemiology of human autoimmune disease
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisMolecular Regulation of Cell Migration and Survival in Lymphoid Tissues
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingRegulation of B Lymphocyte and Macrophage Function by Cell Surface Receptors
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyBacterial host-Cell Interactions
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyImmunopathogenesis of Asthma; Genomics of Disease
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyMechanism Oriented Clinical Research in Airway Disease
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisImmunopathogenesis of HIV and malaria in childhood
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingImmunobiology of Dendritic Cells in Disease
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyMolecular Analysis of HIV Pathogenesis
Primary Research Interest: Vascular & Cardiac BiologySecondary Research Interest: ImmunologyMetabolic Changes and the Host Response to Infection
Primary Research Interest: ImmunologySecondary Research Interest: Vascular & Cardiac BiologyLipoproteins and Immune Responses to Infection and Acute Injury
Primary Research Interest: ImmunologySecondary Research Interest: Vascular & Cardiac BiologyRole of Innate Immune Pathways in Sepsis and Critical Illness
Primary Research Interest: Immunology
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyImmune recognition and control of malaria
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: ImmunologyThe Intersection between Dietary Lipids, Inflammation, and Metabolic Disease
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingMolecular Coordination in Multipartite Interactions
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingNK cell receptors in viral immunity, tumor immunity, and autoimmunity
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisHIV Pathogenesis
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: ImmunologyMetabolism and Regulation of Nitric Oxide Bioactivity
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisAnalysis of vertebrate immunity in vivo
Primary Research Interest: Tissue/Organ Biology & EndocrinologySecondary Research Interest: ImmunologyMechanisms of lung inflammation and injury
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingTyrosine Kinase Regulated Signal Transduction in Blood Cells
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyHuman Microbiome, Chronic Inflammatory Disease
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingUbiquitination and Innate Immunity
Primary Research Interest: ImmunologySecondary Research Interest: Developmental & Stem Cell BiologyTolerance induction after in utero stem cell transplantation or gene therapy
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisLymphocyte Migration and Autoimmune Disease
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyPathogenic Mechanisms, Treatment, and Prevention of HIV Disease
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyBiochemistry, Immunopathogenesis and Molecular Biology of Parasitic Diseases
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: ImmunologyGenetic analysis of signal transduction in B cell development and leukemia
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisCellular immune responses to HIV
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyMolecular Pathogenesis of HIV and Hepatitis C Virus Infections
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisMolecular biology of MHC II and HIV
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisCellular immune dysfunction during persistent viral infections
Primary Research Interest: ImmunologySecondary Research Interest: Human GeneticsInherited disorders of lymphocyte development
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: ImmunologyRas Signal Transduction in Lymphocytes and Cancer
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingRoles of biological sulfation in leukocyte trafficking and tumorigenesis
Primary Research Interest: Cancer Biology & Cell SignalingSecondary Research Interest: Immunology
Primary Research Interest: ImmunologySecondary Research Interest: Virology & Microbial PathogenesisInterplay between anti- and pro-inflammatory cytokines in adaptive immunity
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingRegulation of Innate Immunity by Cell Surface Receptors
Primary Research Interest: Human GeneticsSecondary Research Interest: ImmunologyPopulation Genetics and Human Genetics of Host Defense, Autoimmune Disease, and Diabetes
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyIn vivo function of integrins and molecular basis of lung diseases
Primary Research Interest: ImmunologyAntigen presentation by dendritic cells and its role in the pathogenesis of asthma
Primary Research Interest: ImmunologyRegulatory T cell control of autoimmunity and transplant rejection
Primary Research Interest: Virology & Microbial PathogenesisSecondary Research Interest: ImmunologyHIV Pathogenesis and lymphocyte biology
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingAutoimmune Disease
Primary Research Interest: ImmunologySecondary Research Interest: Cancer Biology & Cell SignalingSignal transduction in lymphocytes
Primary Research Interest: ImmunologyMechanisms of autoimmunity
Primary Research Interest: ImmunologySecondary Research Interest: Tissue/Organ Biology & EndocrinologyCellular and molecular pathogenesis of lung disease
Primary Research Interest: ImmunologySecondary Research Interest: Human GeneticsGenomics of Obstructive Lung Diseases
Primary Research Interest: ImmunologySecondary Research Interest: NeurobiologyPathogenesis and immune modulation of CNS autoimmunity