Peter Turnbaugh, PhD

Associate Professor
Department of Microbiology and Immunology
G.W. Hooper Research Foundation
Chan Zuckerberg Biohub
+1 415 502-3237

Our lab is an interdisciplinary group of microbiome researchers committed to understanding host-associated microbes, reducing these complex microbial ecologies to molecular mechanism, and applying these lessons to improve the practice of medicine. We are currently focused on two major areas: pharmacology and nutrition. We use a variety of inter-disciplinary approaches ranging from the molecular (biochemistry and bacterial genetics) to the organismal (gnotobiotic mice, conventional animals, and human cohorts) to the ecological (synthetic microbial communities and metagenomic sequencing).

Primary Thematic Area: 
Virology & Microbial Pathogenesis
Secondary Thematic Area: 
Immunology
Research Summary: 
Impact of the human gut microbiome on pharmacology and nutrition

Websites

Featured Publications: 

Diet rapidly and reproducibly alters the human gut microbiome.

Nature

David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, Ling AV, Devlin AS, Varma Y, Fischbach MA, Biddinger SB, Dutton RJ, Turnbaugh PJ

Predicting and manipulating cardiac drug inactivation by the human gut bacterium Eggerthella lenta.

Science (New York, N.Y.)

Haiser HJ, Gootenberg DB, Chatman K, Sirasani G, Balskus EP, Turnbaugh PJ

The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice.

Science translational medicine

Turnbaugh PJ, Ridaura VK, Faith JJ, Rey FE, Knight R, Gordon JI

A core gut microbiome in obese and lean twins.

Nature

Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE, Sogin ML, Jones WJ, Roe BA, Affourtit JP, Egholm M, Henrissat B, Heath AC, Knight R, Gordon JI