September 17, 2009

Speaker 1: Amy Heidersbach
Talk Title
Suzuki H.I. et al. Modulation of microRNA processing by p53. Nature.  vol 460. p 529-533. (23 July 2009)
Coaches: Deepak Srivastava and Scott Oakes

Speaker 2: Robert Blelloch (faculty)
"Ends Do Matter"
Mayr C. and Bartel D.P. Widespread Shortening of 3UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells. Cell. 138: 673-684 (2009)

September 24, 2009

Speaker 1: Megan Salt
"Salamander Limb Regeneration: Can you teach an old cell new tricks?"
Kragl M. et al. Cells keep a memory of their tissue origin during axolotl limb regeneration. Nature. Vol 460. July 2, 2009. pp.60-65. 
Coaches: Miguel Ramalho-Santos and Tamara Alliston

Speaker 2: Elliott Sherr (faculty)
"Life without GPS: Draxin, a repulsive guidance protein for spinal cord and forebrain commissures"
Shahidul M. Islam, et al. Draxin, a Repulsive Guidance Protein for Spinal Cord and Forebrain Commissures. Science 323:388 - 393 (2009)

October 1, 2009

Speaker 1: Nir Oksenberg
"Morpholino...more like MophoHERO"
Wheeler T.M. et al.Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA. Science 2009 Jul 17 325 (5938):336-9
Coaches: Alan Frankel and Nadav Ahituv

Speaker 2: Marta Margeta (faculty)
"Spineless but not wishy-washy: miR-138, APT1, and dendritic spine morphogenesis"
Siegel G et al.: A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol 11:705-16, 2009.

October 8, 2009

Speaker 1: Todd Logan
"Bringing down the hammer on Parkinson's Disease: The translation inhibitor Thor smites dopaminergic neurodegeneration in Drosophila"
Tain L.S. et al. Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss. Nature Neuroscience 12, 1129 - 1135 (2009)
Coaches: Jayanta Debnath and Steven Finkbeiner

Speaker 2: Davide Ruggero (faculty)
"Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment"
Schafer Z. et al. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature 461:109-113, 2009.

October 15, 2009

Speaker 1: Fong Koh
"5' UTR matters too!"
Zid et al. 4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila. Cell (2009) (139) pp.149-160
Coaches: Andrei Goga and Davide Ruggero

Speaker 2: David Erle (faculty)
"Lungs taste bitter"
Shah A.S. et al. Motile Cilia of Human Airway Epithelia Are Chemosensory. Science 28 August 2009: Vol. 325. no. 5944, pp. 1131 - 1134

October 22, 2009

Speaker 1: Mantissa Johnston
"Eternal Memory of the Aged Mind"
Perineuronal Nets Protect Fear Memories from Erasure. Gogolla N. et al. Science 4 September 2009. Vol. 325. no. 5945, pp. 1258 - 1261
Coaches: Erik Ullian and Dan Lim

Speaker 2: Erik Ullian (faculty)
"Making contacts in all the right places"
Stringent specificity in the construction of a GABAergic presynaptic inhibitory circuit. Betley et al., 2009 Cell 139:161-174

Speaker 2: Dean Sheppard (faculty)
"The toll road to asthma goes through the epithelium"
House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Hammad H. et al. Nat Med 2009 Apr 15(4):410-6.

November 5, 2009

Speaker 1: Alex Greer
"Tom and Jerry Take on Allergies!"
Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy Journal of Experimental Medicine 206(9): 1941-1955.
Coaches: Jeoung-Sook Shin and Qizhi Tang

Speaker 2: Harold Bernstein (faculty)
"Can the human heart truly be an ISLand?"
Bu L et al. (2009) Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature 460:113-117.

November 12, 2009

Speaker 1: Jasmine Lau
"(Cork)Screwing Your Long-Term Memory"
The Phosphatase SHP2 Regulates the Spacing Effect for Long-Term Memory Induction. Cell. 2009 Oct 2;139(1):186-98.
Coaches: Ben Braun and Eric Rulifson

Speaker 2: Mary Premenko-Lanier (faculty)
“The Mighty B Demands the Spotlight”
Multiple layers of B cell memory with different effector functions. Dogan I, et al.
Nature Immunology. 2009 Oct 25.

November 19, 2009

Speaker 1: Todd Metzger
TBA
Chaundhry A et al. CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner. Science. 2009 Oct 1
Coaches: Mark Anderson and Jeff Bluestone

Speaker 2: Jay Debnath (faculty)
NFKB: An Achilles Heel in K-Ras-driven Cancers
Requirement for NF-kB signalling in a mouse model of lung adenocarcinoma. Meylan, Etienne, et al. Nature 5 November 2009. Vol. no. 462, pp. 104-108

November 26, 2009

NO JOURNAL CLUB
Thanksgiving Holiday

December 3, 2009

Speaker 1: Phillips Huang
A Luminal Epithelial Stem Cell That is a Cell of Origin for Prostate Cancer
Wang, X., et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. 2009. Nature 461, 495-500.
Coaches: Martin McMahon and Davide Ruggero

Speaker 2: Mark Ansel (faculty)
Talk Title
Paper Reference

December 10, 2009

Speaker 1: Brett Johnson
Talk Title
Paper Reference
Coaches: TBA

Speaker 2: Holly Ingraham (faculty)
Talk Title
Paper Reference

December 24, 2009

NO JOURNAL CLUB
Winter Holiday

January 28, 2010
Special Admission Day Presentation, 5:00 p.m.
Location: N-225

Speaker 1: Candia Kenific
Talk Title
Paper Reference
Coaches: TBA

Speaker 2: Diane Barber (faculty)
Talk Title
Paper Reference.

February 4, 2010

Speaker 1: Josh Faguet (MSTP)
Talk Title
Paper Reference
Coaches: TBA

Speaker 2: Scott Oakes (faculty)
Talk Title
Paper Reference

February 11, 2010
Special Admission Day Presentation, 5:00 p.m.
Location: N-225

Speaker 1: Megan McSweeney
Talk Title
Paper Reference
Coaches: TBA

Speaker 2: Abul Abbas (faculty)
Talk Title
Paper Reference.

March 25, 2010

NO JOURNAL CLUB
Cesar Chavez Holiday