Todd McDevitt, PhD

Senior Investigator, Gladstone Institute
Professor
Department of Bioengineering and Therapeutic Sciences
+1 415 734-2875
Research Overview: 

Dr. McDevitt is a Senior Investigator at the Gladstone Institute of Cardiovascular Disease and a Professor of Bioengineering and Therapeutics at the University of California, San Francisco. He was previously the founding Director of the Stem Cell Engineering Center at Georgia Tech, the Carol Ann and David D. Flanagan Professor in the Wallace H. Coulter Department of Biomedical Engineering, and a Petit Faculty Fellow in the Parker H. Petit Institute for Bioengineering and Bioscience. Dr. McDevitt has 18 years of experience in biomaterials and tissue engineering research and for the past 14 years has focused primarily on stem cell biology and engineering. One of the primary objectives of Dr. McDevitt’s research is to engineer tissues, largely from stem cell sources, for regenerative medicine and in vitro diagnostic applications. Much of the research in the McDevitt laboratory focuses on the application of microtechnologies to engineer 3D environments in order to more effectively control multicellular organization that better recapitulates complex tissue structure and subsequent function.

Publications: 

Loss of TJP1 disrupts gastrulation patterning and increases differentiation toward the germ cell lineage in human pluripotent stem cells.

Developmental cell

Vasic I, Libby ARG, Maslan A, Bulger EA, Zalazar D, Krakora Compagno MZ, Streets A, Tomoda K, Yamanaka S, McDevitt TC

Engineering multicellular living systems-a Keystone Symposia report.

Annals of the New York Academy of Sciences

Cable J, Arlotta P, Parker KK, Hughes AJ, Goodwin K, Mummery CL, Kamm RD, Engle SJ, Tagle DA, Boj SF, Stanton AE, Morishita Y, Kemp ML, Norfleet DA, May EE, Lu A, Bashir R, Feinberg AW, Hull SM, Gonzalez AL, Blatchley MR, Montserrat Pulido N, Morizane R, McDevitt TC, Mishra D, Mulero-Russe A

Diseased, differentiated and difficult: Strategies for improved engineering of in vitro neurological systems.

Frontiers in cellular neuroscience

Elder N, Fattahi F, McDevitt TC, Zholudeva LV

Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system.

Open biology

Natarajan V, Simoneau CR, Erickson AL, Meyers NL, Baron JL, Cooper S, McDevitt TC, Ott M

Self-Assembled Heterotypic Cardiac Spheroids from Human Pluripotent Stem Cells.

Methods in molecular biology (Clifton, N.J.)

Matthys OB, McDevitt TC