Raymond Swanson, MD

Professor in Residence
Department of Neurology
+1 415 750-2011
Research Description: 

Ray Swanson is a clinician-scientist with joint appointments in the UCSF Department of Neurology and the San Francisco Veterans Affairs Medical Center. His research explores bioenergetics and oxidative signaling in neurological disease. His studies in the area of stroke aim to identify ways to mitigate the dendritic and axonal ischemic injury, and in particular injury caused by neuronal NADPH oxidase and cofilin-actin rod formation. Work pertaining to Parkinson's disease aims to identify interactions between neuronal redox state and alpha-synuclein aggregation. This effort also involves pre-clinical and clinical studies of thiol repletion agents as a disease-modifying therapeutic approach. The Swanson laboratory is in the 1700 Owens St. building on the Mission Bay campus.

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
None
Research Summary: 
Bioenergetics and oxidative signaling in neurological disease

Websites

Publications: 

Cofilactin rod formation mediates inflammation-induced neurite degeneration.

Cell reports

Uruk G, Mocanu E, Shaw AE, Bamburg JR, Swanson RA

Bioenergetic and excitotoxic determinants of cofilactin rod formation.

Journal of neurochemistry

Mai N, Wu L, Uruk G, Mocanu E, Swanson RA

Brain energy metabolism: A roadmap for future research.

Journal of neurochemistry

Rae CD, Baur JA, Borges K, Dienel G, Díaz-García CM, Douglass SR, Drew K, Duarte JMN, Duran J, Kann O, Kristian T, Lee-Liu D, Lindquist BE, McNay EC, Robinson MB, Rothman DL, Rowlands BD, Ryan TA, Scafidi J, Scafidi S, Shuttleworth CW, Swanson RA, Uruk G, Vardjan N, Zorec R, McKenna MC

Use of Botulinum Toxin for Limb Immobilization for Rehabilitation in Rats with Experimental Stroke.

Biomolecules

Zhang H, Liu J, Bingham D, Orr A, Kawabori M, Kim JY, Zheng Z, Lam TI, Massa SM, Swanson RA, Yenari MA

Neuronal Oxidative Stress Promotes a-Synuclein Aggregation In Vivo.

Antioxidants (Basel, Switzerland)

Won SJ, Fong R, Butler N, Sanchez J, Zhang Y, Wong C, Tambou Nzoutchoum O, Huynh A, Pan J, Swanson RA