Dorit Ron, PhD

Professor In Residence
Department of Neurology
+1 415 502-7068

Dr. Ron is a graduate of the School of Pharmacy at the Hebrew University Jerusalem, Israel. She obtained her PhD in Pharmacology from the Hebrew University Jerusalem. She then did her postdoctoral training at The University of California, San Francisco (UCSF) and Stanford University studying the role of scaffolding proteins in signal transduction under the mentorship of Prof. Daria Mochly-Rosen. She has been at the Ernest Gallo Research Center at UCSF for over 10 years. Dr. Ron is a Professor in the Department of Neurology at UCSF and a member of the Neuroscience Graduate Program. She is also the Endowed Chair in Cell Biology of Addiction in Neurology at UCSF, the Scientific Director for a P50 NIH-NIAAA Center Grant and the Director of Intramural Programs at the Ernest Gallo Research Center. She is a recipient of three NIH RO1 grant awards, and is an Associate Editor for the Journal of Neuroscience, Addiction Biology, the Alcohol Journal, as well as a field editor for Alcoholism: Clinical and Experimental Research.

Dr. Ron's research focuses on the molecular neurobiology of alcohol use disorders for which her laboratory uses molecular, electrophysiological and rodent behavior approaches. Dr. Ron's areas of expertise are: molecular neuroscience, signal transduction, neurobiology of addiction and psychiatric disorders. She has published extensively in high impact factor journals such as Proceedings of the National Academy of Sciences USA, the Journal of Neuroscience, FASEB Journal, Biological Psychiatry, the Journal of Biological Chemistry and many others. Over the years her group has made several major contributions to the field of addiction and identified novel targets that could potentially be developed as therapeutics to treat alcohol addiction. Several of her studies resulted in UCSF press releases which received the attention of both the scientific community and the general public.

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Molecular neurobiology of drug addiction

Websites

Featured Publications: 

Protein tyrosine phosphatase a in the dorsomedial striatum promotes excessive ethanol-drinking behaviors.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ben Hamida S, Darcq E, Wang J, Wu S, Phamluong K, Kharazia V, Ron D

Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse.

Nature neuroscience

Barak S, Liu F, Ben Hamida S, Yowell QV, Neasta J, Kharazia V, Janak PH, Ron D

Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Wang J, Ben Hamida S, Darcq E, Zhu W, Gibb SL, Lanfranco MF, Carnicella S, Ron D

Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Barak S, Carnicella S, Yowell QV, Ron D

AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors.

Biological psychiatry

Neasta J, Ben Hamida S, Yowell QV, Carnicella S, Ron D

Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Wang J, Ben Hamida S, Darcq E, Zhu W, Gibb SL, Lanfranco MF, Carnicella S, Ron D

Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Barak S, Carnicella S, Yowell QV, Ron D

AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors.

Biological psychiatry

Neasta J, Ben Hamida S, Yowell QV, Carnicella S, Ron D

Lyn kinase regulates mesolimbic dopamine release: implication for alcohol reward.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Gibb SL, Jeanblanc J, Barak S, Yowell QV, Yaka R, Ron D

Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders.

Proceedings of the National Academy of Sciences of the United States of America

Neasta J, Ben Hamida S, Yowell Q, Carnicella S, Ron D

Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Wang J, Carnicella S, Ahmadiantehrani S, He DY, Barak S, Kharazia V, Ben Hamida S, Zapata A, Shippenberg TS, Ron D

Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Wang J, Lanfranco MF, Gibb SL, Yowell QV, Carnicella S, Ron D