Atul Butte, MD, PhD

Professor
Department of Pediatrics
+1 415 514-0528

Atul Butte, MD, PhD is the Priscilla Chan and Mark Zuckerberg Distinguished Professor and inaugural Director of the Institute for Computational Health Sciences (ichs.ucsf.edu) at the University of California, San Francisco (UCSF). Dr. Butte is also the Executive Director for Clinical Informatics across the six University of California Medical Schools and Medical Centers. Dr. Butte has authored over 200 publications, with research repeatedly featured in the New York Times, Wall Street Journal, and Wired Magazine. Dr. Butte was elected into the National Academy of Medicine in 2015, and in 2013, he was recognized by the Obama Administration as an Open Science Champion of Change for promoting science through publicly available data. Dr. Butte is also a founder of three investor-backed data-driven companies: Personalis, providing medical genome sequencing services, Carmenta (acquired by Progenity), discovering diagnostics for pregnancy complications, and NuMedii, finding new uses for drugs through open molecular data. Dr. Butte is a principal investigator of three major programs: the California Initiative to Advance Precision Medicine; ImmPort, the clinical and molecular data repository for the National Institute of Allergy and Infectious Diseases; and the California Precision Medicine Consortium, helping recruit tens of thousands of participants into President Obama's Precision Medicine Initiative. Dr. Butte trained in Computer Science at Brown University, worked as a software engineer at Apple and Microsoft, received his MD at Brown University, trained in Pediatrics and Pediatric Endocrinology at Children's Hospital Boston, then received his PhD from Harvard Medical School and MIT.

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Immunology
Research Summary: 
Dr. Butte builds and applies tools that convert more than 400 trillion points of molecular, clinical, and epidemiological data into diagnostics, therapeutics, and new insights into disease.
Publications: 

Precision annotation of digital samples in NCBI's gene expression omnibus.

Scientific data

Hadley D, Pan J, El-Sayed O, Aljabban J, Aljabban I, Azad TD, Hadied MO, Raza S, Rayikanti BA, Chen B, Paik H, Aran D, Spatz J, Himmelstein D, Panahiazar M, Bhattacharya S, Sirota M, Musen MA, Butte AJ

Big data opens a window onto wellness.

Nature biotechnology

Butte AJ

Cancer Cell-Autonomous Parainflammation Mimics Immune Cell Infiltration.

Cancer research

Lasry A, Aran D, Butte AJ, Ben-Neriah Y

RImmPort: an R/Bioconductor package that enables ready-for-analysis immunology research data.

Bioinformatics (Oxford, England)

Shankar RD, Bhattacharya S, Jujjavarapu C, Andorf S, Wiser JA, Butte AJ