Amar Nijagal, MD
Our lab is studying the intersection and relationship between immunology and fetal development. Specifically, we are interested in understanding the role of the maternal immune system in regulating the developmental pathways that guide fetal tissue and organ formation. We have chosen to focus our investigations on maternal microchimerism, which is the naturally occurring phenomenon by which maternal cells travel into the fetus during pregnancy. Our hope is to understand the basic biology of maternal microchimerism and determine whether maternal immune cells influence fetal development.
The major goals of our laboratory are:
- To characterize the types and localization of maternal immune cells in the fetus
- To understand how maternal cellular trafficking into the fetus is regulated
- To determine the function of maternal cells in the fetus and whether they play a role in regulating fetal tissue development