Biomedical Sciences Graduate Program | University of California, San Francisco

Biomedical Sciences (BMS) Graduate Program

Fall Core Courses

BMS 260 Cell Biology
BMS 225A Tissue/Organ Biology

Winter Core Courses

BMS 255 Genetics
BMS 225B Tissue/Organ Biology

Spring Core Courses

Mini-Courses

Events

BMS 198 Journal Club
BMS Seminars
Other Events

Electives (partial list)

Micro 204 Immunology (fall)
BMS 220 Stem Cell Biology (spring)
Graduate Course Listings Pages

BMS Courses

Micro 209. The science of immunological diseases: translating basic research to the clinic.

Course Directors
Abul Abbas, MD; Averil Ma, MD; Mark Anderson, MD, PhD.

Course description
This course will discuss the pathogenesis of selected immune-mediated inflammatory diseases, and the clinical features and therapeutic approaches for these diseases. At the end of the course, students are expected to have a better appreciation of: the links between basic immunology and the development of immunological diseases; the application of animal models to understanding disease pathogenesis; modern technologies for studying patients; and the principles underlying rational drug design and development for inflammatory diseases. Students taking this course are expected to have basic knowledge of Immunology.

Components of the course
Sessions will consist of lectures, discussion of seminal papers (in the format of student-run journal clubs), and interviews with patients. Students will be assigned to discuss the journal club papers; these assignments will be handed out on the first day of the course. Please note that it is essential to maintain confidentiality when you interview patients, and to be appropriately respectful of individuals who are willing to share their lives with us. Attendance at all sessions is required; if you are unable to attend a session for some reason, please inform one of the co-directors.

Evaluation
At the end of the course, students will be asked to take an exam that will consist of short essay-type answers and possibly a brief paper on one of several topics to be assigned.

Schedule
Days: Mondays
Time: 1:30 p.m. - 3:30 p.m.
Location: N-721, Parnassus

Journal Club Assignments (revised 10/3/2008)

Date	Lecturer	Lecture Topic	Downloads
9/22/2008	Abul Abbas MD, Professor & Chair of Pathology	Introduction: Self-tolerance, autoimmunity and immune-mediated inflammatory diseases.	Lecture
9/29/2008	John Imboden MD, Professor of Medicine	Rheumatoid arthritis I. Basic science: Pathogenesis; discussion of two selected papers.	Lecture Paper 1 Paper 2
10/6/2008	John Imboden MD, Professor of Medicine Jonathan Graf, MD, Assistant Professor of Medicine	Rheumatoid arthritis II. Clinical aspects, clinical features, therapies. (lecture at 1:30pm) Rheumatoid arthritis: patient interview at 2:30pm	Lecture
10/20/2008	Averil Ma MD, Professor of Medicine	Inflammatory bowel disease I. Basic science: Pathogenesis; discussion of two selected papers.	Lecture (revised 10/20/08) Paper 1 Paper 2
10/27/2008	Fernando Velayos MD, Assistant Professor of Medicine	Inflammatory bowel disease II . Clinical aspects: clinical features, therapies, patient interview.	Lecture
11/3/2008	Mark Anderson MD, PhD, Assistant Prof. of Medicine	Type 1 diabetes I. Basic science: Pathogenesis; discussion of two selected papers.	Lecture Paper 1 Paper 2
11/3/2008	Steve Gitelman	Type 1 diabetes II. Clinical aspects: clinical features, therapies, patient interview.	Lecture
11/17/2008	Steve Hauser MD, Professor & Chair of Neurology	Multiple sclerosis I. Basic science: Pathogenesis; discussion of two selected papers.	Lecture Paper 1 Paper 2
11/24/2008	Ari Green, MD Assistant Prof of Neurology	Multiple sclerosis II. Clinical aspects: clinical features, therapies, patient interview.
12/1/2008	Andrew Chan MD, PhD Vice-President, Genentech	Novel immune therapies: rational drug design based on scientific principles.